Please call the American Lung Association Lung HelpLine at 1-800-LUNGUSA for. However, researchers expect to conduct further research comparing the effects of different MSC sources and routes of administration in an effort to increase therapeutic measures. Via EurekAlert: 'When autologous (self-donated) lung-derived mensenchymal stem cells (LMSCs) were transplanted endoscopically into 13 adult female sheep modeled with emphysema, post-transplant evaluation showed evidence of tissue regeneration with increased blood perfusion and extra cellular matrix content. The American Lung Association has recently signed onto a statement along with a number of respiratory and thoracic societies, outlining the potential dangers and risks in using unregulated stem cell treatments for respiratory diseases. The study found that after the mice had been injected with stem cells from bone marrow, adipose and/or lung tissue, there were “increased elastic fiber content and reduced alveolar-capillary membrane,” which allows for the regeneration of damaged lung and cardiovascular tissue.Īlthough the study results illustrate the benefits of stem cell use in induced emphysema, the experiment has not been conducted on humans and there currently is not have a timetable for doing so. Sacs inside them called alveoli grow too large. The regenerative approaches have included extrinsic cell therapy such as the infusion of exogenous stem cells to repair the damaged structure of the respiratory system and intrinsic cell therapy such as the administration of small molecules to stimulate the endogenous lung stem/progenitor cells for regeneration and replacement of the damaged structures). Regenerative Medicine often employs the use of Stem Cell Therapy for COPD, which has the potential to replace many different cell types throughout the body. Over many years, your lungs become damaged and diseased. This enlargement is often accompanied by a decrease in pulmonary regeneration, which can lead to chronic obstructive pulmonary disease (COPD). Emphysema is one of the major health problems involved in COPD. Researchers, who induced emphysema in mice, aimed to determine if injection of MSCs into various points of delivery, both intra-tracheal and intravenous, would reduce the lungs’ alveoli from becoming enlarged. Results indicate that lung and cardiovascular damage in research mice was reduced based on various types of MSC injections. New Stem Cell Research Offers Insights into Novel Emphysema TherapiesĪ new study published in Respiratory Research, studied the impact of different mesenchymal stem cells (MSCs) in the treatment emphysema.
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